Prednivex 4/Prednivex 16 Adverse Reactions

Fluid and Electrolyte Disturbances: Sodium retention.
Congestive heart failure in susceptible patients: Hypertension, Fluid retention, Potassium loss, Hypokalemic alkalosis.
Musculoskeletal: Muscle weakness, Loss of muscle mass, Steroid myopathy, Osteoporosis, Vertebral compression fractures, Aseptic necrosis of femoral and humeral heads, Pathologic fracture of long bones.
Gastrointestinal: Peptic ulcer with possible perforation and hemorrhage.
Pancreatitis: Abdominal distention, Ulcerative esophagitis.
Dermatologic: Impaired wound healing, Petechiae and ecchymoses. May suppress reactions to skin tests. Thin fragile skin, Facial erythema, Increased sweating.
Neurological: Increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment, Convulsions, Vertigo, Headache.
Endocrine: Development of Cushingoid state; Suppression of growth in children; Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness; Menstrual irregularities; Decreased carbohydrate tolerance; Manifestations of latent diabetes mellitus; Increased requirements for insulin or oral hypoglycemic agents in diabetics.
Ophthalmic: Posterior subcapsular cataracts, Increased intraocular pressure, Glaucoma, Exophthalmos.
Metabolic: Negative nitrogen balance due to protein catabolism.
The following additional reactions have been reported following oral as well as parenteral therapy: Urticaria and other allergic, anaphylactic or hypersensitivity reactions.